The New York Giants and the Dallas Cowboys square off in a game that many could immediately predict what the result will be.

The Giants are 2-7 with a boatload of injuries on their roster. New York traded defensive lineman Leonard Williams at the trade deadline for two draft picks, which was a strong indication that its focus is on the future. Plus, the Giants placed quarterback Tyrod Taylor on IR before last week’s contest against the Las Vegas Raiders. Meanwhile, Daniel Jones tore his ACL against the Raiders and is out for the season. That leaves third-string rookie Tommy DeVito getting starting snaps. A season full of promise coming off a playoff win last year is now in ruins.

On the other side, the Cowboys sit at 5-3 and second in the NFC East behind the Philadelphia Eagles. Dallas is coming off a 28-23 loss to Philadelphia, but it has an offense that has shown true explosion. The Cowboys are also a juggernaut at home, scoring at least 30 in three easy wins over the Jets, Patriots, and Rams.

This Sunday’s tilt between two NFC East squads is a rematch from Week 1, where the Cowboys handled the Giants 40-0 on Sunday Night Football at MetLife Stadium. In that game, the Giants were at full health. Now with the state of New York as it is, what do the Giants vs. Cowboys odds have in store? Ahead of this Week 10 matchup, here are the best bets to make.

GIANTS VS. COWBOYS ODDS: Don’t Shy Away From Dallas -16

This line on DraftKings may seem daunting on the surface. While it would be a two score game to match that 16-point line, essentially the bet is on Dallas to win by three scores. However, when you look at who the opponent is, it is realistic to believe that the Cowboys can win by three scores.

Remember, the Cowboys dominated in all three phases against the Giants in Week 1 en route to a 40-point shutout. Plus, just last week, where DeVito played a good chunk of that game as the signal caller, New York fell to Las Vegas 30-6–a 23-point difference. The Raiders had just fired their head coach and were playing their first game under interim head coach Antonio Pierce.

Dallas has a potent offense led by Dak Prescott and CeeDee Lamb, as well as a disruptive defense led by Micah Parsons. This Giants offense has a lot of holes on offense with injuries on the offensive line and a third-string quarterback starting.

Think of it another way. The Giants have scored over 16 points just once this year. Even if they get to 16, Dallas would need 33 to cover. That seems very doable. Don’t be afraid of the line and lay the points.

Latest Giants vs. Cowboys Odds at NY Sportsbooks
Bet $5, Get $150 in Bonus Bets
4.5 rating

Highest-Scoring Team in the NFL on Sunday: Dallas (+700)

This is a fun bet to place on the Cowboys offense that has shown true signs of explosion recently. Dak Prescott and company are capable of putting up points in bunches. While the offense was held to 23 points a week ago on the road against a tough Philly defense, Dallas has scored at least 30 points four times this season. In two of those matchups, the Cowboys have hit the 40-point mark. This is an offense that can explode.

In that offense, receiver CeeDee Lamb has been playing like he is on a mission recently. The former Oklahoma Sooner has had three consecutive 100-yard games. He pulled in 11 receptions for 191 yards last week. That production alone should give fans optimism that this Cowboys offense can score points quickly.

The Giants just gave up 30 points to the Raiders that were led by rookie quarterback Aidan O’Connell, who was the third-string signal caller entering the regular season. Plus, the Giants have given up 30 points or more four times this season.

And we haven’t even talked about the Cowboys’ defense and special teams. Each unit scored against the G-Men in week 1. Take this bet on FanDuel and watch the points pile up.

New York Giants vs. Dallas Cowboys Totals Bet: Take the Over at 38.5

Taking the over in this matchup is solely contingent on how the Cowboys offense performs. With Dak Prescott, CeeDee Lamb, and tight end Jake Ferguson, who has had a touchdown in each of the last two contests, this offense can eclipse the 38.5-point mark on its own. 

With DeVito leading the charge, it might be tough to trust the Giants offense to score, which is why this line of 38.5 might seem too low. With that, though, trust the Cowboys to dominate the Giants when they have the ball, and take this totals bet on PointsBet

Bet Week 10 of the 2023 NFL season at NY Sportsbooks
Bet $5 Get $150 in Bonus Bets
If Your Bet Wins
5.0 rating

Top Sportsbooks 2023
5.0 rating
Bet $5 Get $150 in Bonus Bets
If Your Bet Wins
4.3 rating
Get Up To $100
In Bonus Bets!
Bonus Code: Sports
3.3 rating
First Bet Offer Up To $1500

BetMGM Sportsbook Welcome Offers Halted in the state of NY! But Available In NJ.
4.8 rating
Bet $50
Get Up To $1000 Back In Bonus Bets
On Caesars
4.5 rating
Bet $5, Get $150 in Bonus Bets