While the Jets enjoy their bye this week, both the Buffalo Bills and New York Giants see themselves as favorites in the NFL Week 10 opening lines.

Moving into Week 10 of the 2022 NFL season, New York state still sees three of the best teams in pro football. While the Jets get to enjoy their Bye Week following one of the franchise’s biggest wins in years, the other two teams will take the field. Both the Bills and Giants see themselves as betting favorites in the NFL Week 10 opening lines.

Some league-wide betting trends seem to have an effect on the NFL Week 10 opening lines. Underdogs maintained their dominant pace, improving to 75-56-5 (57.3 percent) against the spread so far. Road underdogs have been particularly good, covering at nearly a 58 percent clip (44-32-2). The Under also continues to roll, going 80-54 through nine weeks of the season.

Here’s a look at the NFL Week 10 opening lines for the two New York teams in action on Sunday.

NFL Week 10 Opening Lines: Buffalo Bills vs Minnesota Vikings

Buffalo couldn’t hold their lead against the Jets and saw its offense flounder in the second half for the second week in a row. Minnesota, meanwhile, rallied behind quarterback Kirk Cousins to top the Washington Commanders on the road last week. Despite that, the Bills remain favorites in the NFL Week 10 opening lines. 

That said, Buffalo might be happy to see its line set in single digits, considering their struggles to cover double-digit spreads of late.

The Bills (6-2, 4-3-1 ATS) welcome Minnesota to western New York for a clash of two competitive teams. The Vikings (7-1, 3-4-1 ATS) have a strangle hold on the NFC North division right now and will likely play as an underdog for just the second time this season. Buffalo, meanwhile, holds just a half-game lead in the AFC East and needs to grab a win here. 

One of the reasons this line has started under a touchdown despite Buffalo being at home is the uncertainty surrounding Bills quarterback Josh Allen. Near the end of last week’s loss, Allen suffered an elbow injury on a strip sack play. Bills head coach Sean McDermott said there was no definitive news on Allen’s status as the team awaits MRI results. 

Allen’s availability will have a significant effect on this line one way or the other. Should Allen miss a significant amount of time to this injury, his NFL MVP odds will continue to fade

Bills Best Odds-6/-107 (PointsBet)-250 (DraftKings)Over 46/-110 (BetMGM)Under 46.5/-107 (PointsBet)

NFL Week 10 Opening Lines: New York Giants vs Houston Texans

The Giants are back from their bye week and are set to host the dreadful Houston Texans at MetLife Stadium on Sunday. Following a tough road loss in Seattle prior to their bye, New York hopes to regain the positive momentum that carried them throughout the first half of the season. 

New York (6-2, 6-2 ATS) sits in third place in the NFC East standings despite their fast start and they’ll need a win here against a hapless Houston team to keep pace with Philadelphia and Dallas. The Texans (1-6-1, 4-3-1 ATS) sit in last place in the AFC South and have entered each week as an underdog. That’s the case here in the NFL Week 10 opening lines, as the Texans are getting nearly a touchdown at most sportsbooks. 

The Giants moneyline stands among the top-5 early plays by total tickets at BetRivers. That’s no surprise considering the state of this Houston squad. That might be the better bet considering Houston enters this one with a 2-1-1 mark against the spread on the road this season. 

Giants Best Odds-6.5/-107 (PointsBet)-275 (FanDuel)Over 39.5/-110 (Caesars)Under 40/-110 (DraftKings)
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