The 2022 Major League Baseball season is down to two teams, the Houston Astros and Philadelphia Phillies. These squads square off in the 2022 World Series with compelling betting odds.

Baseball bettors finally know the final matchup of the season: Houston versus Philadelphia. Sunday saw both league championship series come to an end, with the Astros sweeping the New York Yankees and the Phillies topping the San Diego Padres. With the World Series matchup set, sportsbooks shifted to providing their latest betting odds and opening lines. 

The Houston Astros push to the World Series comes on the back of a 7-0 run to start the 2022 MLB playoffs. The Astros making it to the Fall Classic shouldn’t be a surprise though, considering Houston stood among the favorites at +1000 to win the World Series to start the season. 

Their National League counterparts, the Philadelphia Phillies, survived a slow start to the season and a managerial change to make their World Series run. Philadelphia’s arrival at the Fall Classic comes as a surprise given those circumstances and their opening odds (+2500) in the spring. 

Here’s a look at the best 2022 World Series betting odds for the Astros and Phillies. 

2022 World Series Betting Odds at New York Sportsbooks

SportsbookHouston Astros oddsPhiladelphia Phillies odds

The Astros entered the postseason with the second-best betting odds to win the World Series at +425. The Phillies, meanwhile, started the playoffs as a longshot, seeing +2500 odds almost across the board. 

Houston enters this series as the favorite, looking to score its second World Series title (2017). The Astros came up short in their previous two World Series runs, losing to the Atlanta Braves last season and the Washington Nationals in 2019. Now they face another NL East opponent on the game’s biggest stage. The Phillies last won the World Series in 2008 (they also won in 1980). Philadelphia’s last trip to the World Series came in 2009, when they lost to the New York Yankees. 

Several betting trends affect the odds in this World Series matchup between the Astros and Phillies. Houston enters the Fall Classic as just the third team to sweep their way through the playoffs to reach the World Series, joining the 2007 Colorado Rockies and 2014 Kansas City Royals. However, both the Rockies and Royals lost those series. 

These two teams did meet in the final regular season series prior to starting the 2022 postseason. The Astros won two of the three matchups, which were played in Houston. Philadelphia covered in two of those games, with the Under hitting in two of the three as well. 

Astros Favorites in World Series Betting Odds 

The Astros rallied in New York in Game 4 of their ALCS with the Yankees. The 6-5 victory gave Houston its fifth pennant in franchise history and now the Astros seek their second World Series title, one that presumably won’t be tainted by a cheating scandal. 

Houston dominated the Yankees this season, going 9-2 against the Bronx Bombers. The Astros continued to have New York’s number in the postseason as well, eliminating the Yankees from the playoffs for the fourth time in the past eight seasons, including ALCS wins in 2017 and 2019. 

The Astros leaned on their pitching throughout the season, finishing second in both team ERA (2.90) and WHIP (1.09). Houston pitchers limited opposing hitters to a .212 batting average, second-lowest in MLB, and Astros relievers registered 53 saves, which led the American League. 

Against New York in the ALCS, Astros starting pitchers surrendered just four earned runs over 23.1 innings pitched. Houston’s bullpen allowed just two earned runs in the series. The Astros pitching staff registered 50 strikeouts during the ALCS. 

While pitching has led the way for the Astros, Houston’s lineup is no slouch. The Astros hit 214 home runs this season, second-most in the AL.

Phillies Remain Longshots in World Series Betting Odds

Philadelphia punched its ticket to the World Series with a dramatic come-from-behind victory in Game 5. Bryce Harper’s two-run home run in the eighth inning put the Phillies ahead for good, helping earn him the NLCS MVP award 

The Phillies opened these playoffs as a longshot, seeing betting odds to win the World Series as long as 45/1 at some sportsbooks. But Philadelphia has defied the odds throughout the season. The team stood at 22-29 after firing manager Joe Girardi earlier this year and installing Rob Thomson as interim. The Phillies finished 87-75, earned one of the NL Wild Card spots, and proceeded on their unlikely run to the World Series. 

The Phillies made MLB’s postseason thanks to the expanded playoff field this season. No team in history has ever made the World Series after finishing third in their division like the Phillies did. According to the daily newsletter Morning Brew, the Phillies winning the World Series directly correlates to economic downturns. 

Philadelphia uses a potent lineup that’s performed well these playoffs. With Harper, Rhys Hoskins, J.T. Realmuto, and Kyle Schwarber anchoring the lineup, the Phillies slugged 205 homers, sixth most in baseball. Philadelphia has hit 16 homers this postseason, most among playoff teams. Their .750 OPS trails only the Toronto Blue Jays, who played just two playoff games before elimination. 

The Phillies pitching staff has been solid in these playoffs, too, posting a 3.06 team ERA and 0.97 WHIP. 

2022 World Series Player Prop Odds

Position players have won 16 of the last 20 World Series MVP honors, including then-Astros outfielder George Springer winning in 2017. Phillies starting pitcher Cole Hamels is one of four starting pitchers to win the MVP award over the last 20 years, doing so when Philadelphia won in 2008. 

PlayerDraftKings MVP OddsFanDuel MVP Odds
Yordan Alvarez, OF+600+650
Bryce Harper, OF+700+700
Justin Verlander, SP+900+1000
Kyle Schwarber, DH+1300+1300
Jose Altuve, 2B+1400+1300
Jeremy Peña, SS +1700+1800

Harper earned NLCS MVP honors with his great play against the Padres. He continues to roll this postseason, slashing .419/.444/.907 with a 10-game hitting streak and five playoff homers. Harper is the betting favorite at Caesars to finish the postseason with the most home runs (+180), a stat he’s currently tied with teammate Rhys Hoskins and Yankees outfielder Harrison Bader. 

A longshot for this award is Astros rookie Jeremy Peña, who enters this Fall Classic after winning the ALCS MVP. While it seems unlikely, Peña finished the ALCS 6-for-17 with two homers and two doubles and became just the fifth rookie since 2015 to hit a homer in multiple playoff series-clinching games. 

The pitcher with the shortest betting odds to win World Series MVP is Astros starter Justin Verlander. The 39-year-old ace dominated the Yankees in Game 1 of the ALCS, allowing just one run and striking out 11 over six innings. He’s the likely Game 1 starter for Houston and could see a second turn in the series, which always helps pitchers in this award. That said, Verlander enters this matchup 0-6 with an ERA of 5.68 and 39 strikeouts in 7 appearances in the World Series in his career. 

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